7 Highly Effective Disinfectant Spray Recipes- good top zone disinfectant spray ,Easy-to-Make Disinfectant Spray Tips & Recipes 1. Homemade Disinfectant Spray. This simple, natural disinfectant is a perfect multi-purpose spray that you can use on almost all surfaces and makes a great glass cleaner. Avoid using this cleaner on marble and granite, as the acid in the vinegar may leave marks.10 Best Hospital Grade DisinfectantsThe Lysol disinfectant spray has the capacity to kill illness-causing germs and viruses without having any harmful effect on you. It works perfectly on hard surfaces like trash cans, light switches, doorknobs, tables, bathtubs, toilet seats, doors, and many others.