Hand Hygiene Recommendations | CDC- how much should the alcohol level be in hand sanitizer in order ,The USP hand sanitizer toolkit external icon formulas have final concentrations of 80% ethanol or 75% isopropyl alcohol concentrations. A final concentration of 80% ethanol or 75% isopropyl alcohol recommended in the USP hand sanitizer toolkit are aligned with World Health Organization (WHO) formulations pdf icon external icon.Hand sanitizers need a certain level of alcohol to be ...Yes, hand sanitizers need to reach a certain alcohol level to be effective in killing the coronavirus. But make sure you properly read the labels.