Hand Hygiene Recommendations | CDC- hand sanitizer alcohol requirement ,The USP hand sanitizer toolkit external icon formulas have final concentrations of 80% ethanol or 75% isopropyl alcohol concentrations. A final concentration of 80% ethanol or 75% isopropyl alcohol recommended in the USP hand sanitizer toolkit are aligned with World Health Organization (WHO) formulations pdf icon external icon.FDA issues further guidance for alcohol and hand sanitizer ...To meet component quality requirements for hand sanitizer production, the alcohol manufactured as an API meets at a minimum the United States Pharmacopoeia (USP) or Food Chemical Codex (FCC) grade requirements for purity, that is, not less than 94.9% ethanol by volume.